Table 2.
Pooled hazard ratios of low lean mass on mortality according to cancer type and measurement index.
| Cancer type | L3 Skeletal Muscle Index |
L3 Psoas Index |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n (no. of studies) | I2 | HR | 95% CI | n (no. of studies) | I2 | HR | 95% CI | |||
| Bile duct (excludes intrahepatic) | 100 (1) | NA | 2.02 | [1.12, 3.65] | 207 (1) | NA | 2.92 | [1.91, 4.47] | ||
| Breast | 325 (3) | 61% | 1.69 | [0.79, 3.58] | NA | |||||
| Gastrointestinal | 8668 (18) | 48% | 1.56 | [1.36, 1.78] | NA | |||||
| Head and neck | 2840 (1) | NA | 1.92 | [1.19, 3.11] | NA | |||||
| Hematopoietic | 259 (3) | 73% | 1.34 | [0.51, 3.53] | NA | |||||
| Liver and intrahepatic bile duct | 2947 (15) | 28% | 2.30 | [1.89, 2.78] | 189 (2) | 0% | 1.71 | [1.03, 2.83] | ||
| Lung | 546 (4) | 49% | 2.69 | [1.50, 4.85] | 161 (1) | NA | 1.17 | [0.66, 2.08] | ||
| Ovarian and endometrium | 740 (4) | 54% | 1.18 | [0.85, 1.64] | 338 (2) | 38% | 1.25 | [0.73, 2.15] | ||
| Pancreatic | 1109 (5) | 0% | 1.65 | [1.38, 1.97] | 1381 (3) | 16% | 1.62 | [1.34, 1.97] | ||
| Prostate | 226 (1) | NA | 0.90 | [0.54, 1.50] | NA | |||||
| Urinary tract | 1529 (10) | 48% | 1.86 | [1.45, 2.38] | 254 (2) | 0% | 2.15 | [1.31, 3.51] | ||
| Mixed | 4293 (5) | 61% | 1.19 | [1.03, 1.38] | NA | |||||
| Overall | 23582 (70) | 65% | 1.66 | [1.52, 1.82] | 2530 (11) | 50% | 1.70 | [1.38, 2.08] | ||
n, number of subjects; HR, hazard ratio; CI, confidence interval; NA, not applicable.