TABLE 3.

Target Attainment Rates for T>MIC of 40% and T>MIC of 100% Using Different Dosing Regimens:

Target Attainment Rates for T>MIC of 40%
	30 minutes infusion					2 hours infusion					4 hours infusion
MIC	20mg/kg q12H	40mg/kg q12H	10mg/kg q8H	20mg/kg q8H	40mg/kg q8H	20mg/kg q12H	40mg/kg q12H	10mg/kg q8H	20mg/kg q8H	40mg/kg q8H	20mg/kg q12H	40mgrkg q12H	10mg/kg q8H	20mg/kg q8H	40mg/kg q8H
0.5	100	100	100	100	100	100	100	100	100	100	100	100	100	100	100
1	100	100	100	100	100	100	100	100	100	100	100	100	100	100	100
2	100	100	100	100	100	100	100	100	100	100	100	100	100	100	100
4	98	100	99	100	100	100	100	100	100	100	100	100	100	100	100
8	89	98	95	99	100	97	100	99	100	100	100	100	100	100	100
16	56	89	56	95	99	79	97	88	99	100	99	100	100	100	100
32	11	56	3	56	95	26	79	12	88	99	72	99	91	100	100
Target Attainment Rates for T>MIC of 100%
	30 minutes infusion					2 hours infusion					4 hours infusion
MIC	20mg/kg q12H	40mg/kg q12H	10mg/kg q8H	20mg/kg q8H	40mg/kg q8H	20mg/kg q12H	40mg/kg q12H	10mg/kg q8H	20mg/kg q8H	40mg/kg q8H	20mg/kg q12H	40mg/kg q12H	10mg/kg q8H	20mg/kg q8H	40mg/kg q8H
0.5	67	81	92	96	98	76	87	96	98	99	87	94	99	100	100
1	51	67	82	92	96	60	76	90	96	98	74	87	97	99	100
2	32	51	60	82	92	39	60	73	90	96	53	74	90	97	99
4	13	32	31	60	82	21	39	45	73	90	31	53	69	90	97
8	3	13	9	31	59	4	21	14	45	73	10	31	30	69	90
16	0	3	1	9	31	0	4	1	14	45	0	10	3	30	68
32	0	0	0	1	8	0	0	0	1	13	0	0	0	3	29

MIC=Minimum Inhibitory Concentration (mg/L); q12h= every 12hours; q8h= every 8hours

Red box indicate the optimal target attainment rates (>90%) for 100% ƒ_{T>MIC= 4}