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. 2021 Apr 19;11:654350. doi: 10.3389/fonc.2021.654350

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Copyright © 2021 Qiu, Tian, He, Li, He, Li, Liu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparisons of CD86 expression with different histological/molecular subtypes of LGG stratified by tumor grade. (A) CD86 expression in astrocytoma, oligoastrocytoma and oligodendroglioma. (B) CD86 expression in IDH mutant and WT of LGG. (C) CD86 expression in MGMT-methylated LGG versus unmethylated type. (D) CD86 expression in LGG with X1p/19q codeletion versus non-codeletion. (E) IHC staining of CD86 among different molecular subtypes regarding status on MGMT methylation and X1p/19q codeletion. *p<0.05 **p<0.01, ***p<0.001, ****p<0.0001, ns: not significant.