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. 2021 Apr 19;11:656496. doi: 10.3389/fcimb.2021.656496

Table 1.

Physicochemical characteristics of organic nanoparticles.

Organic NPs REF Functional group Diameter (nm) ζ - potential (mV) Tested uropathogens Activity
Aminocellulose nanospheres (Macedo et al., 2017) Primary amine 268 ± 7 103 ± 2 E. coli Antibiofilm
Aminocellulose nanospheres/hyaluronic acid construct (Francesko et al., 2016) Hyaluronic acid 268 ± 7 103 ± 2 P. aeruginosa Antibiofilm
Glycerol monolaurate nanocapsules (Lopes et al., 2019) 190.7 ± 2 -23.3 ± 3 P. aeruginosa Antibiofilm
Chlorhexidine-loaded poly(ε-caprolactone) nanospheres (Phuengkham and Nasongkla, 2015) poly(ε-caprolactone) 198.8 ± 6.9 S. aureus, S. epidermidis and E. coli Antibacterial
Chlorhexidine-loaded poly(ε-caprolactone) nanospheres (Srisang and Nasongkla, 2019) poly(ε-caprolactone) 152 ± 37 40.21 ± 1.08 E. coli, S. aureus, and C. albicans Antibacterial
Polyurethane chlorhexidine nanocomposites (Francesko et al., 2016) S. epidermidis Antibacterial
Kanamycin-chitosan nanoparticles (Venkat Kumar et al., 2016) NA 225 36 E. coli and P. mirabilis Antibacterial
Antibiofilm
Chlorin e6 encapsulated charge-conversion polymeric nanoparticles (Lui et al., 2015) poly (β-amino ester)s 33.5 ± 4.5 -6 S. aureus and E. coli Antibacterial
chitosan-coated poly(lactide-co-glycolide) nanoparticles loaded with amphotericin B (Ludwig et al., 2018) poly(lactide-co-glycolide) 459 ± 22 18 ± 3.5 Candida sp. Antifungal
Nano catechin (Yoon et al., 2011) 100 – 200 E. coli Antibacterial
Polyphenol 60 and curcumin nanoemulsion based gel (intravaginal) (Kaur et al., 2017a) 211.2 -32.7 UPEC Antibacterial
polyphenol 60 + cranberry nanoemulsion based gel (intravaginal) (Kaur et al., 2017b) 58 -16 E. coli Antibacterial
Polyphenol 60 and ciprofloxacin (Atinderpal et al., 2018) 151.7 55.3 E. coli, K. pneumoniae, P. mirabilis, C. amalonatus and C. diversus Antibacterial
Bilayer nanocapsules containing lutA antigen (vaccine) (Crecente-Campo et al., 2018) 200 ± 2 42 ± 4 E. coli, K. pneumoniae, P. mirabilis, C. amalonatus and C. diversus Vaccine