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. 2021 Apr 19;11:640268. doi: 10.3389/fonc.2021.640268

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Copyright © 2021 Hou, Zhang, Yang, Wu, Wang, Zhang, Yang, Hou, Wu, Wang, Dong, Guo, Shi and Ling

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan-Meier survival curves and decision curves for T1–2 breast cancer with 1–3 positive lymph nodes. Survival curves in the entire cohort before PSM (A) and after PSM (B) stratified by the total score of the nomogram. 3-year (C), 5-year (D), 10-year (E) decision curves show that nomogram and its risk stratification have the highest net benefit almost across the entire threshold probabilities. Blue line: net benefit of a strategy of treating all T1–2 breast cancer with 1–3 positive lymph nodes. Gray line: net benefit of treating no patients of T1–2 breast cancer with 1–3 positive lymph nodes. Colored lines: net benefit of a strategy of treating patients according to the nomogram, risk stratification, grade, and positive nodes.