Table 3.
Characteristic | Low-risk group | Moderate-risk group | High-risk group | ||||||
---|---|---|---|---|---|---|---|---|---|
Control cohort(3211) | PMRT cohort(3211) | SMD | Control cohort(2117) | PMRT cohort(2117) | SMD | Control cohort(771) | PMRT cohort(771) | SMD | |
Marital Status | 0.009 | 0.011 | -0.003 | ||||||
Married | 2559(79.7) | 2584(80.5) | 1211(57.2) | 1209(57.1) | 265(34.4) | 261(33.9) | |||
USDW | 652(20.3) | 627(19.5) | 906(42.8) | 908(42.9) | 506(65.6) | 510(66.1) | |||
Age (years) | -0.005 | -0.016 | -0.021 | ||||||
20-39 | 453(14.1) | 485(15.1) | 300(14.2) | 332(15.7) | 82(10.6) | 77(10.0) | |||
40-49 | 1499(46.7) | 1437(44.8) | 511(24.1) | 475(22.4) | 57(7.4) | 83(10.8) | |||
50-59 | 995(31.0) | 1028(32.0) | 647(30.6) | 644(30.4) | 218(28.3) | 196(25.4) | |||
60-69 | 264(8.2) | 261(8.1) | 659(31.1) | 666(31.5) | 414(53.7) | 415(53.8) | |||
Race | -0.006 | -0.001 | 0.027 | ||||||
White | 2519(78.4) | 2466(76.8) | 1649(77.9) | 1641(77.5) | 549(71.2) | 526(68.2) | |||
Black | 192(6.0) | 232(7.2) | 317(15.0) | 323(15.3) | 198(25.7) | 218(28.3) | |||
Other | 500(15.6) | 513(16.0) | 151(7.1) | 153(7.2) | 24(3.1) | 27(3.5) | |||
Grade | 0.003 | 0.012 | 0.005 | ||||||
1 | 503(15.7) | 477(14.9) | 72(3.4) | 72(3.4) | 7(0.9) | 11(1.4) | |||
2 | 1679(52.3) | 1686(52.5) | 740(35.0) | 734(34.7) | 108(14.0) | 112(14.5) | |||
3 | 1029(32.0) | 1048(32.6) | 1305(61.6) | 1311(61.9) | 656(85.1) | 648(84.0) | |||
T stage | -0.002 | 0.001 | 0.007 | ||||||
T1 | 1613(50.2) | 1613(50.2) | 453(21.4) | 445(21.0) | 61(7.9) | 65(8.4) | |||
T2 | 1598(49.8) | 1598(49.8) | 1664(78.6) | 1672(79.0) | 710(92.1) | 706(91.6) | |||
Chemotherapy | 0.004 | 0.002 | 0.001 | ||||||
No | 190(5.9) | 174(5.4) | 186(8.8) | 181(8.5) | 100(13.0) | 100(13.0) | |||
Yes | 3021(94.1) | 3037(94.6) | 1931(91.2) | 1936(91.5) | 671(87.0) | 671(87.0) | |||
Examined lymph nodes | -0.001 | 0.009 | -0.018 | ||||||
≤12 | 1546(48.1) | 1503(46.8) | 1174(55.5) | 1154(54.5) | 486(63.0) | 483(62.6) | |||
>12 | 1665(51.9) | 1708(53.2) | 943(44.5) | 963(45.5) | 285(37.0) | 288(37.4) | |||
Positive lymph nodes | -0.013 | -0.007 | -0.014 | ||||||
1 | 1650(51.4) | 1682(52.4) | 844(39.9) | 862(40.7) | 216(28.0) | 243(31.5) | |||
2 | 1151(35.8) | 1118(34.8) | 753(35.6) | 726(34.3) | 246(31.9) | 201(26.1) | |||
3 | 410(12.8) | 411(12.8) | 520(24.6) | 529(25.0) | 309(40.1) | 327(42.4) | |||
ER | -0.002 | -0.009 | -0.008 | ||||||
Negative | 176(5.5) | 185(5.8) | 677(32.0) | 702(33.2) | 515(66.8) | 515(66.8) | |||
Positive | 3035(94.5) | 3026(94.2) | 1440(68.0) | 1415(66.8) | 256(33.2) | 256(33.2) | |||
PR | -0.006 | -0.017 | -0.030 | ||||||
Negative | 398(12.4) | 424(13.2) | 966(45.6) | 999(47.2) | 611(79.2) | 623(80.8) | |||
Positive | 2813(87.6) | 2787(86.8) | 1151(54.4) | 1118(52.8) | 160(20.8) | 148(19.2) |
USDW, unmarried/separated/divorced/widowed; Other, American Indian/AK Native, Asian/Pacific Islander; grade 1, well differentiated; grade 2, moderately differentiated; grade 3, poorly differentiated/undifferentiated; ALND, axillary lymph node dissection; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; SMD, standardized mean difference.