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. 2021 Apr 7;28:133–140. doi: 10.1016/j.ctro.2021.03.010

Table 1.

Baseline patient, tumor, and treatment characteristics of the overall cohort stratified by NLR ≤ 4.0 and NLR > 4.0 groups.

Variable All Patients (N = 389) NLR ≤ 4.0 (N = 275) NLR > 4.0 (N = 114) P value
Pretreatment NLR <0.0001*
Median (range) 3.0 (0.4–42) 2.4 (0.4–4) 5.3 (4.1–42)
Age 0.24
Median (range) 71 (49–93) 71 (49–93) 72 (53–90)
Gender 0.99
Male 378 (97.2%) 267 (97.1%) 111 (97.4%)
Female 11 (2.8%) 8 (2.9%) 3 (2.6%)
Charlson Score 0.46
0 83 (21.3%) 61 (22.1%) 22 (19.3%)
1 141 (36.2%) 103 (37.5%) 38 (33.3%)
2+ 165 (42.5%) 111 (40.4%) 54 (47.4%)
Race 0.01*
White 335 (86.1%) 229 (83.3%) 106 (93.0%)
Black 54 (13.9%) 46 (16.7%) 8 (7.0%)
Smoker at Diagnosis 0.74
Yes 167 (42.9%) 120 (43.6%) 47 (41.2%)
No 222 (57.1%) 155 (56.4%) 67 (58.8%)
Histology 0.42
Adenocarcinoma 162 (41.6%) 120 (43.6%) 42 (36.9%)
Squamous 156 (40.1%) 105 (38.2%) 51 (44.7%)
Other/unknown 71 (18.3%) 50 (18.2%) 21 (18.4%)
T stage
< 2 cm (T1a) 166 (42.7%) 118 (42.9%) 48 (42.1%) 0.57
2-3 cm (T1b) 143 (36.8%) 104 (37.8%) 39 (34.2%)
3-5 cm (T2a) 80 (20.5%) 53 (19.3%) 27 (23.7%)
Total BED (Gy10) 0.96
Median (range) 112.5 (100–187.5) 112.5 (100–187.5) 112.5 (100–180)
White Blood Cell Count (K/μL) <0.0001*
Median (range) 8.0 (2.9–22.5) 7.5 (2.9–22.5) 9.1 (5–22.1)
Absolute Neutrophil Count (K/μL) <0.0001*
Median (range) 5.1 (0.8–19.6) 4.5 (0.8–12.1) 6.7 (2.6–19.6)
Absolute Lymphocyte Count (K/μL) <0.0001*
Median (range) 1.6 (0.1–13.5) 1.8 (0.4–13.5) 1.2 (0.1–12.5)
Pretreatment FEV1 (N = 229) (N = 162) (N = 67) 0.96
≤ 30% 22 (9.6%) 15 (9.3%) 7 (10.5%)
31-50% 71 (31.0%) 49 (30.2%) 22 (32.8%)
51-80% 103 (45.0%) 74 (45.7%) 29 (43.3%)
> 80% 33 (14.4%) 24 (14.8%) 9 (13.4%)