Table 2.
Multivariable a priori regressions on overall survival (OS), lung cancer-specific survival (LCS), non-lung cancer survival (NCS) in the overall cohort.
| Variable | OS |
LCS |
NCS |
|||
|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| NLR | ||||||
| ≤ 4.0 | 1.0 | 1.0 | 1.0 | |||
| > 4.0 | 1.44 (1.12–1.86) | 0.01* | 1.32 (0.95–1.82) | 0.09 | 1.68 (1.11–2.53) | 0.01* |
| Age | 1.03 (1.02–1.05) | 0.0001* | 1.03 (1.02–1.05) | 0.0004* | 1.03 (1.01–1.06) | 0.01* |
| Gender | ||||||
| Male | 1.0 | 1.0 | 1.0 | |||
| Female | 0.98 (0.59–1.62) | 0.93 | 1.11 (0.53–2.32) | 0.78 | 0.80 (0.31–2.08) | 0.65 |
| Charlson Score | ||||||
| 0 | 1.0 | 1.0 | 1.0 | |||
| 1 | 1.35 (0.98–1.86) | 0.07 | 1.56 (1.03–2.36) | 0.04* | 1.05 (0.62–1.78) | 0.85 |
| 2+ | 1.56 (1.13–2.16) | 0.01* | 1.50 (0.97–2.32) | 0.07 | 1.68 (1.02–2.78) | 0.04* |
| Race | ||||||
| White | 1.0 | 1.0 | 1.0 | |||
| Black | 0.73 (0.51–1.04) | 0.08 | 0.84 (0.56–1.28) | 0.43 | 0.57 (0.30–1.07) | 0.08 |
| Smoker at Diagnosis | ||||||
| Yes | 1.0 | 1.0 | 1.0 | |||
| No | 0.80 (0.63–1.02) | 0.07 | 0.89 (0.66–1.20) | 0.46 | 0.70 (0.45–1.02) | 0.06 |
| Histology | ||||||
| Adenocarcinoma | 1.0 | 1.0 | 1.0 | |||
| Squamous | 1.04 (0.80–1.33) | 0.79 | 1.23 (0.89–1.70) | 0.20 | 0.78 (0.52–1.18) | 0.24 |
| Other/unknown | 0.86 (0.59–1.24) | 0.41 | 1.05 (0.66–1.67) | 0.84 | 0.61 (0.33–1.15) | 0.13 |
| T stage | ||||||
| < 2 cm (T1a) | 1.0 | 1.0 | 1.0 | |||
| 2–3 cm (T1b) | 1.32 (1.02–1.72) | 0.04* | 1.41 (1.01–1.96) | 0.04* | 1.20 (0.77–1.87) | 0.42 |
| 3–5 cm (T2a) | 1.25 (0.91–1.70) | 0.16 | 1.23 (0.83–1.82) | 0.31 | 1.29 (0.79–2.11) | 0.31 |
| Total BED | 1.00 (0.99–1.00) | 0.49 | 1.00 (0.99–1.00) | 0.32 | 1.00 (0.99–1.01) | 0.92 |