Table 3.

Clinical Trials of CGM Use in ICU Settings for Pediatric Patients

Study	Year	First author country	Population	Type of CGM	CGM manufacturer	Performance measurement	Comparator
Bridges et al. [69]	2010	USA	ICU (n=47)	Guardian	Medtronic MiniMed	Accuracy	Arterial, venous, and capillary by iSTAT POC and lab
Steil et al. [70]	2011	USA	Cardiac ICU (n=311)	Guardian	Medtronic MiniMed	Accuracy and hypoglycemia prevention	Arterial by POC and lab
Prabhudesai et al. [71]	2015	UK	ICU (n=19)	Guardian	Medtronic MiniMed	Accuracy	Arterial by lab
Kotzapanagiotou et al. [72]	2020	Greece	ICU (n=16)	FreeStyle Libre	Abbott Diabetes Care	Accuracy	Arterial by blood gas analyzer capillary by POC, biochemical serum by lab
Sopfe et al. [73]	2020	USA	Stem cell transplantation (n=29)	FreeStyle Libre Pro	Abbott Diabetes Care	Accuracy	Central venous by lab
Garelli et al. [68]	2020	Argentina	ICU patients with COVID-19 (n=2) (3 other adult patients were also studied)	Dexcom G6 for the ICU patients	Dexcom	Glycemic control using a new multisensor platform	None
Chesser et al. [74]	2021	USA	Children with postprandial hypoglycemia due to late dumping syndrome following gastric surgeries (n=3)	Dexcom G4 Dexcom G5 Dexcom G6	Dexcom	Diagnose hypoglycemia due to late dumping syndrome. Also to determine best treatment strategies and feeding regimens.	None

AID, automated insulin delivery; CGM, continuous glucose monitoring; ICU, intensive care unit; POC, point of care; COVID-19, coronavirus disease 2019.