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. 2021 Mar 2;24(2):153–163. doi: 10.4048/jbc.2021.24.e15

Table 2. Accumulating cardiotoxicity occurrence rate.

Items M0 M3 M6 M9 M12 M15
Heart failure 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Acute coronary syndrome 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (1.4)
Life-threatening arrhythmias 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
ΔLVEF ≥ 10% and LVEF < 53% - 0 (0.0) 6 (8.3) 9 (12.5) 11 (15.3) 12 (16.7)
Cardiotoxicity - 0 (0.0) 6 (8.3) 9 (12.5) 11 (15.3) 12 (16.7)

Values are presented as number (%).

M0 = before initiation of adjuvant therapy; M3 = 3 months after initiation of adjuvant therapy; M6 = 6 months after initiation of adjuvant therapy; M9 = 9 months after initiation of adjuvant therapy; M12 = 12 months after initiation of adjuvant therapy; M15 = 15 months after initiation of adjuvant therapy; LVEF = left ventricular ejection fraction; ΔLVEF = absolute decline of LVEF from M0.