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. 2021 Apr 25;246(14):1643–1649. doi: 10.1177/15353702211008106

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© 2021 by the Society for Experimental Biology and Medicine

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Hypothetical target mechanism of gene manipulation to combat against deadly SARS-CoV-2-mediated infection. The schematic diagram represents the possible mechanism of gene manipulation by CRISPR/Cas13d and PAC-MAN via degradation of specific target sequence of SARS-CoV-2 to inhibit the viral replication to protect the human health. (A color version of this figure is available in the online journal.)