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. 2021 May 3;67(2):481–491. doi: 10.1007/s10620-021-06922-6

Table 4.

Sub analysis of patients with clinical improvements

Sub-analysis of those with improvements* Median change (IQR) Change in step count
Decreased Maintained Increased
Weight loss (lb) 15^ (45.5%) − 7 (− 12.9, − 2) 2 9 2
≥ 5% weight loss 6 (18.2%)
Reduction in ALT (U/L) 17^ (51.5%) − 30 (− 78, − 11) 2 12 2
Reduction to < 35 10 (33.3%)
Reduction in TG (mg/dL) 21 (63.6%) − 2.5 (− 6.5, − 0.3) 4 14 3
Reduction to < 150 9 (31%)
Reduction in liver stiffness (kPa) 14^ (42.4%) − 12 (− 26, − 6) 2 10 1
 ≥ 10% Reduction in kPa 7 (30.4%)
Reduction in CAP (dB/m) 14^ (42.4%) − 46 (− 85, − 20) 3 13 2
 ≥ 10% Reduction in CAP 7 (50%)
Increase in 6MWT (feet) 23^ (69.6%) 140 (35–255) 4 14 3
6MWT > population mean 5 (17.9%)

Bolded values indicate result was significant with P value of 0.05 or less

*Top row for each variable represents number of participants with any improvement for that variable. Second row for each variable represents number of participants with more marked improvement

^2 patients missing 6-month step count data for weight loss and 6MWT; 1 patient had missing 6-month step count data for reduction in ALT, kPa and CAP