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. 2021 Apr 19;12:641848. doi: 10.3389/fphar.2021.641848

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Copyright © 2021 Song, Feng, Zhang, Deng, Yu, Zhang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Tanshinone IIA on polarization-related mRNA expressions after OGD in BV2 cells. OGD-induced BV2 cells were treated with Tanshinone IIA. Quantitative RT-PCR was used to assess the mRNA expression levels of M1 microglia markers: CD11b (A), CD32 (B), iNOS (C), and M2 microglia markers: Arg-1 (D), CD206 (E), IL-10 (F). ##p < 0.01, compared with the Con group, *p < 0.05, compared with the OGD group. Con, control group; OGD, oxygen-glucose deprivation; TanIIA, Tanshinone IIA. BAY, BAY-11-7082, a NF-κB inhibitor, n = 3.