Relationship between differentially expressed proteins at days 1, 5, and 28 postinfection in the CSF of C. acnes- infected animals. (A) A Venn diagram depicts the similarities and differences between significantly differentially expressed proteins in the CSF of C. acnes-infected animals compared to sterile catheters at all time points, as determined by MS analysis. Significant proteins for each time point are presented in Tables S1 to S3 in the supplemental material. (B) A Venn diagram dipicts the overlap between significantly differentially expressed proteins in the CSF at days 1, 5, and 28 postinfection.