FIG 5.
Persistence over time of intragastrically administered Lp900 in adult male rats. (A) Persistence of Lp900-R in rats on Lca (open circles) and LcaInu (filled circles) diets after a single gavage with approximately 8 × 109 CFU of L. plantarum Lp900-R on day 0. (B) Persistence of Lp900-R in rats on Hca (open circles) and HcaInu (filled circles) diets after a single gavage with approximately 8 × 109 CFU of L. plantarum Lp900-R on day 0. (C) Persistence of Lp900-R in rats on Lca diets receiving a probiotic (LcaP; open circles) (9 × 109 CFU of Lp900-R) or synbiotic (LcaS; filled circles) (9 × 109 CFU of Lp900-R in a 27.5% [wt/vol] Orafti GR inulin solution). (D) Persistence of LP900-R in rats on Hca diets receiving a probiotic (HcaP; open circles) (9 × 109 CFU of Lp900-R) or synbiotic (HcaS; filled circles) (9 × 109 CFU of Lp900-R in a 27.5% [wt/vol] Orafti GR inulin solution). All CFU counts are log transformed and expressed as means ± the SEM (n = 8 per diet group). Asterisks indicate at which time points the inulin supplemented (either by diet or gavage) are significantly different than the respective control group as detected by a two-sided nonparametric Mann-Whitney U test with α = 0.05 (*, P < 0.05; **, P < 0.01; ***, P < 0.001).
