FIG 1.

Serologic response to noncanonical antigens following natural infection. (A) Heat map of log₂-transformed Z-score data indicating ETEC protein microarray responses from days 2 and 30 following presentation to the icddr,b to four noncanonical antigens, EtpA, YghJ, the passenger domain of EatA, and EaeH, and the B subunit of ETEC heat-labile toxin (LT-B). (B) Kinetic ELISA responses to EtpA and EatA following infection. Data are segregated by the presence or absence of the respective antigen in the strain recovered at presentation. Negative-control samples from St. Louis Children’s Hospital (slch) are shown as open circles. *, P < 0.05 by a Wilcoxon matched-pairs signed-rank test.