Table 1.
Start of study | End of study | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Case | Viral Load | NRTIs detected | NNRTIs detected | Major NRTI mutations | Major NNRTI mutations | Viral Load | NRTIs detected | NNRTIs detected | PIs detected | Major NRTI mutations | Major NNRTI mutations |
1 | 18,900 | 3TC | NVP | M184V | K103N | <400 | 3TC, TDF | - | ATV/r | N/A | N/A |
2 | 480 | 3TC, TDF | EFV | - | K103N | <400 | 3TC, TDF | EFV | - | N/A | N/A |
3 | 34,100 | - | - | - | K103N | <400 | 3TC, TDF | EFV | - | N/A | N/A |
4 | 1,180 | - | - | - | K103N | <400 | FTC, TDF | EFV | - | N/A | N/A |
5 | 8,440 | - | - | - | K103N | <400 | FTC, TDF | EFV | - | N/A | N/A |
6 | 43,200 | - | - | - | Y188C | 34,720 | - | - | - | - | - |
7 | 195,990 | - | - | - | K103N, G190A | 4,770 | - | - | - | - | K103N |
8 | 17,520 | - | EFV | M184I | K103N, V106M | 1,280 | FTC, TDF | EFV | - | L74V, M184V | K103N, V106M |
9 | 430 | - | EFV | - | - | 4,510 | FTC, TDF | EFV | - | K65R | K103N, Y188C |
10 | 48,100 | - | - | - | - | 21,910 | 3TC, TDF | EFV | - | K65R | K103N, V106M |
The table shows results of antiretroviral drug testing and HIV drug resistance testing. Testing was performed at the start of the study (screening visit) and at the end of the study (12-month visit). Results are shown only for participants who had HIV drug resistance mutations detected at one or both visits. HIV viral load values are shown as copies/mL. HIV drug resistance testing was not performed at 12 months for five virally suppressed participants (N/A).
Abbreviations: NRTI, nucleoside/nucleotide reverse transcriptase inhibitor; NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor; 3TC, lamivudine; TDF, tenofovir disoproxil fumarate; FTC, emtricitabine; NVP, nevirapine; EFV, efavirenz; ATZ, atazanavir; and r, ritonavir.