Table 2.
Evaluation of the secondary outcomes by between-group analyses
| Secondary outcomes | Group | Time-points | |||
|---|---|---|---|---|---|
| Week 1 mean ± s.d. |
Month 1 mean ± s.d. |
Month 3 mean ± s.d. |
Month 6 mean ± s.d. |
||
| BVCA (logMAR) | A | 0.50 ± 0.51 | 0.26 ± 0.16 | 0.20 ± 0.21 | 0.19 ± 0.18 |
| B | 0.55 ± 0.32 | 0.37 ± 0.26 | 0.31 ± 0.24 | 0.28 ± 0.23 | |
| p-value | n.s. | n.s. | n.s. | n.s. | |
| IOP (mmHg) | A | 17.7 ± 7.0 | 16.1 ± 2.4 | 15.9 ± 3.0 | 15.5 ± 2.6 |
| B | 13.7 ± 3.3 | 15.4 ± 4.9 | 14.9 ± 3.3 | 14.2 ± 3.5 | |
| p-value | < 0.001 | n.s. | n.s. | n.s. | |
| CMT (μm) | A | – | 279 ± 26 | 270 ± 26 | 270 ± 25 |
| B | – | 278 ± 30 | 316 ± 118 | 297 ± 91 | |
| p-value | – | n.s. | 0.01 | n.s. | |
| LOCS III | A | 0.35 ± 0.75 | 0.54 ± 0.90 | 0.73 ± 1.15 | 1.31 ± 1.74 |
|
p-value vs baseline |
n.s | n.s | n.s | 0.003 | |
BCVA Best-corrected visual acuity, IOP Intraocular pressure, CMT Central macular thickness (by Optical Coherence Tomography), LOCS III Lens Opacities Classification System III scale