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. Author manuscript; available in PMC: 2022 Apr 30.
Published in final edited form as: J Mol Biol. 2021 Mar 5;433(9):166885. doi: 10.1016/j.jmb.2021.166885

Figure 5. HnRNP A1/A2 Proteins Bind Stably to the Upper Surface of SL3 to Form a Specific Complex.

Figure 5.

(A) Comparison of the pair distance distribution P(r) functions of free SL3M (Black) and stoichiometric 1:1 (Red), 2:1 (Blue), and 4:1 (Green) UP1-SL3M complexes resolved by inline SEC-MALS-SAXS reveal that hnRNP A1/A2 proteins interact stably with the upper surface of SL3. (B) Comparison of the SAXS molecular reconstructions for free SL3M (Purple), its stoichiometric 1:1 (Red) and 2:1 (Blue) UP1-SL3M complexes.