Table 7.

Univariate analysis of risk factors for culture-negative periprosthetic joint infection

Variable	Odds ratio	95% confidence interval	p value
Age	1.01	0.99–1.05	0.33
Gender (female)	0.53	0.22–1.28	0.16
Comorbidity
Hypertension	1.07	0.44–2.61	0.87
Diabetes mellitus	1.84	0.61–5.58	0.28
Renal insufficiency	1.86	0.50–6.94	0.35
Liver cirrhosis	1.16	0.28–4.71	0.84
Cardiovascular disease	0.73	0.19–2.81	0.65
COPD	1.01	0.10–10.2	0.99
Rheumatoid arthritis	2.68	0.66–10.8	0.17
ASA physical status	0.63	0.18–2.14	0.46
Type of infection (Chronic)	0.53	0.21–1.32	0.18
Prior antimicrobial therapy	0.80	0.33–1.93	0.62
Serum WBC (×103)	0.80	0.65–0.98	0.028*
CRP	0.89	0.77–1.02	0.087
ESR	0.99	0.97–1.00	0.075
D-dimer	1.05	0.88–1.25	0.60
Fluid sample	0.82	0.49–1.38	0.45

COPD chronic obstructive pulmonary disease, ASA American Society of Anesthesiologists, WBC white blood cell, CRP C-reactive protein, ESR erythrocyte sedimentation rate

^*p value < 0.05