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. 2021 Apr 6;11(5):1452–1464. doi: 10.1002/2211-5463.13153

Fig. 1.

Fig. 1

Compound screening using SeV and iPSCs. (A) Construction of SeV. SeV carrying EGFP gene in the 3’ region of viral genomic RNA was constructed after removal of F gene. (B) Timeline of compound screening. (C) Schema of compound screening. (D and E) Result of first screening. Approximately 500 compounds were evaluated. Blue dot shows negative control (DMSO). Red dots show the hit drugs raloxifene, rifampin, pranlukast, zileuton, and pioglitazone. (F) List of hit compounds. The scores reflect the number of EGFP‐positive cells.