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. 2021 Mar 11;87(7):e03137-20. doi: 10.1128/AEM.03137-20

FIG 3.

FIG 3

Transcriptional modulation of B. breve PRL2020 genes in the presence of AMC. The heatmap displays the subset of significantly upregulated encoding genes. Red boxes highlight the ORFs PRL2020_1181, PRL2020_1167, and PRL2020_1282, which are putatively involved in the AMC resistance mechanism. The color scale (green) at the top of the figure indicates increased transcription levels compared to those of the reference samples. The EggNOG letter for each significant upregulated gene is reported. Each letter stands for a function, as follows: S, function unknown; L, replication, recombination, and repair; R, general function prediction only; G, carbohydrate transport and metabolism; J, translation, ribosomal structure, and biogenesis; E, amino acid transport and metabolism; K, transcription; P, inorganic ion transport and metabolism; C, energy production and conversion; V, defense mechanisms; T, signal transduction mechanisms; H, coenzyme transport and metabolism; and I, lipid transport and metabolism.