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Estimation of the total number of SARS-CoV-2 infected shedders, including symptomatic, presymptomatic, asymptomatic, and undiagnosed cases. A model was developed based on the genome copies at the wastewater treatment plants detected during the first wave of the pandemic using the E target; the reported numbers of genome copies excreted in feces were also determined by employing the E target (11) and considering the actual daily wastewater flow.
