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IC50 and EC50 values of hit compounds in SARS-CoV-2 3CLpro and SARS-CoV-2.
| Compound | Structure | IC50 (μM) | EC50 (μM) | Compound | Structure | IC50 (μM) | EC50 (μM) |
|---|---|---|---|---|---|---|---|
| 1 |  |
8.7 ± 0.8 | NA | 2 |  |
10.9 ± 0.8 | NA |
| 3 |  |
8.0 ± 1.4 | 140.9 ± 3.80 | 4 |  |
9.5 ± 0.7 | NA |
| 5 |  |
12.1 ± 2.4 | NA | 6 |  |
8.9 ± 0.8 | NA |
| 7 |  |
5.7 ± 1.1 | 39.89 ± 0.17 | Remdesivir | NA | 11.1 |
