Table 1.

The chemical structure of the analyzed compounds and their IC₅₀ values. The IC₅₀ are expressed as mean ± SEM obtained from three independent experiments and calculated based on the dose-response curves assessed by the MTT assay (COXIBs and 2,5-DMC), or taken from the literature (TMZ)

Compound	IC50 [μM] ± SEM			Chemical structure
	A-172	T98G	U-138 MG
Celecoxib	41 ± 7.11	49 ± 1.34	74 ± 0.99
2,5-dimethylcelecoxib (2,5-DMC)	23 ± 2.25	32 ± 4.86	33 ± 1.72
Etoricoxib	> 100	> 100	> 100
Rofecoxib	> 100	> 100	> 100
Valdecoxib	> 100	> 100	> 100
Temozolomide (TMZ)	<  100	> 1000	387.3