TABLE 2.
Group | Measurement | Result (range) for (%): |
||||
---|---|---|---|---|---|---|
Test A | Test B | Test C | Test D | PCR (serum)b | ||
Overall cohort (n = 370) | Sensitivity | 69.6 (63.2–75.3) | 86.6 (81.5–90.5) | 84.8 (79.4–89.0) | 78.3 (72.4–83.3) | 93.1 (88.9–95.8) |
Specificity | 89.5 (83.7–93.5) | 92.2 (86.8–95.5) | 90.9 (85.2–94.5) | 81.1 (74.1–86.5) | ||
Primary infection setting (n = 236) | Sensitivity | 72.3 (65.6–78.2) | 87.2 (81.7–91.3) | 86.2 (80.5–90.4) | 83.0 (77.0–87.7) | 94.7 (90.4–97.1) |
Specificity | 89.6 (77.8–95.5) | 93.8 (83.2–97.9) | 91.7 (80.5–96.7) | 91.7 (80.5–96.7) | ||
High anti-MeV-IgG avidity setting (n = 134) | Sensitivity | 51.7 (34.4–68.6) | 82.8 (65.5–92.4) | 75.9 (57.9–87.8) | 48.3 (31.4–65.6) | 82.8 (65.5–92.4) |
Specificity | 89.5 (82.2–94.1) | 91.4 (84.5–95.4) | 90.5 (83.4–94.7) | 76.2 (67.2–83.3) |
Diagnostic indices were calculated grading “borderline” results as “negative” using the cutoffs according to the manufacturer.
Diagnostic indices were calculated using PCR from any material as positive reference.