Table 1.
Characteristics | All Patients, n=200 | Urine Protein-Creatinine Ratio, g/g | Urine Retinol Binding Protein-Creatinine Ratio, mg/mmol | ||
---|---|---|---|---|---|
<1, n=116 | ≥1, n=84 | <0.03, n=32 | ≥0.03, n=53 | ||
Men | 143 (71) | 78 (67) | 65 (77) | 21 (65) | 39 (76) |
Age, yr | 63 (54–73) | 60 (53–69) | 67 (55–79) | 59 (48–64) | 63 (54–75) |
BMI, kg/m2a | 26.7 (24.3–30.1) | 26.5 (23.9–30.3) | 27.4 (24.6–30.1) | 26.1 (24.5–30) | 27.6 (24.5–31.3) |
Hypertension | 103 (51) | 53 (46) | 50 (59) | 12 (37) | 29 (55) |
Diabetes | 51 (25) | 25 (21) | 26 (31) | 7 (22) | 16 (30) |
CKD | 18 (9) | 10 (9) | 8 (9) | 2 (6) | 5 (9) |
Use of ACEi or ARB | 60 (30) | 25 (21) | 35 (41) | 7 (22) | 20 (38) |
Use of diuretics | 42 (21) | 19 (16) | 23 (27) | 5 (16) | 10 (19) |
First symptoms to admission, d | 7 (5–9) | 7 (6–9.7) | 7 (4–8) | 7 (4–9) | 7 (5–10) |
UPCR, g/g | 0.86 (0.38–1.50) | 0.41 (0.25–0.72) | 1.6 (1.3–2.1) | 0.24 (0.15–0.51) | 1.22 (0.75–1.8) |
UACR, mg/gb | 110 (50–410) | 60 (20–100) | 480 (260–830) | 98 (42–382) | 250 (103–533) |
UACR-UPCR,b % | 18 (9.6–33.4) | 13 (6.7–20.5) | 32 (20.9–43.3) | 16 (8.5–27.6) | 23 (13.2–36.6) |
URBPCR,c mg/mmol | 0.31 (0–2.76) | 0 (0–0.14) | 2.8 (1–5.8) | 0 (0–0) | 1.35 (0.63–4.8) |
Serum creatinine, mg/dl | 0.94 (0.75–1.21) | 0.85 (0.69–1.12) | 1.03 (0.85–1.36) | 0.83 (0.63–1.11) | 0.98 (0.77–1.30) |
Quantitative values are given as medians (interquartile ranges), and qualitative values are given as number of patients/percentage. BMI, body mass index; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; UPCR, urine protein-creatinine ratio; UACR, urine albumin-creatinine ratio; URBPCR, urine retinol binding protein-creatinine ratio.
Data available for 171 patients.
Data available for 152 patients.
Data available for 85 patients.