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. 2021 Apr 19;11:658636. doi: 10.3389/fonc.2021.658636

Table 8.

Prognostic roles of 5-FU-related lncRNAs (ANTm adjacent normal tissue; OS, overall survival; RFS, relapse-free survival).

Sample Kaplan–Meier Multivariate Cox regression analysis Ref
48 pairs of CRC and ANTs Higher expression of HOTAIR was related to lower OS and RFS rates. Higher expression of HOTAIR was related to tumor size, distant metastasis, and tumor differentiation. (124)
73 pairs of CRC and ANTs Higher expression of PCAT6 was related to a lower OS rate. Higher expression of HOTAIR was related to TNM stage, tumor differentiation, and lymph node metastasis. (126)
119 pairs of CRC and ANTs Higher expression of UCA1 was related to a lower OS rate. Higher expression of UCA1 was related to tumor size and lymph node invasion. (130)
268 pairs of CRC and ANTs Higher expression of XIST was related to lower OS and RFS rates. Higher expression of XIST was related to TNM stage and distant metastasis. (131)
124 pairs of CRC and ANTs Higher expression of TUG1 was related to lower RFS rate. Higher expression of TUG1 was related to the depth of the tumor. (132)
27 pairs of CRC and ANTs Lower expression of HAND2-AS1 was related to lower OS rate. (133)
108 pairs of CRC and ANTs Higher expression of LINC00152 was related to lower OS and DFS rates. Higher expression of LINC00152 was related to the tumor stage. (134)
110 pairs of CRC and ANTs Higher expression of H19 was related to lower RFS rate. (135)
168 pairs of GC and ANTs Higher expression of HOTAIR was related to lower OS rate. Higher expression of HOTAIR was related to tumor size and TNM stage. (143)