TABLE 1.
Clinical and microbial characteristics of screening animals
Clinical parameter or microbial characteristic | Result for macaque: |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
RM1 | RM2 | RM3 | RM4 | RM5 | RM6 | RM7 | RM8 | RM9 | RM10 | |
Clinical parameters | ||||||||||
Nugent score | 9 | 9 | 8 | 5 | 10 | 8 | 7 | 2 | 5 | NCa |
>20% clue cells | Yes | Yes | Yes | No | Yes | Yes | Yes | No | No | NC |
Vaginal pH | 7 | 7.5 | 5.5 | 7.5 | 7 | 7.5 | 5.5 | 6 | 4.5 | 8 |
16S amplicon relative abundance | ||||||||||
Leptotrichiaceae (Sneathia) | 27.26 | 21.26 | 30.52 | 89.78 | 9.7 | 9.37 | 0.36 | 2.78 | 2.13 | 0.05 |
Lactobacillus | 0.02 | 0 | 0 | 0.13 | 0.03 | 0.03 | 42.98 | 55.75 | 84.44 | 0.1 |
Prevotella | 14.84 | 5.02 | 13.58 | 0 | 7.46 | 8.41 | 4.97 | 0.25 | 0.02 | 0.02 |
Mobiluncus | 10.53 | 14.97 | 3.07 | 0 | 7.01 | 8.16 | 0.46 | 0.62 | 0.01 | 0 |
Gardnerella | 0 | 0 | 0 | 0 | 1.17 | 0 | 0 | 6.01 | 8.29 | 0 |
Porphyromonas | 6.66 | 10.78 | 11.08 | 0.29 | 2.95 | 5.18 | 0.32 | 0.36 | 0 | 8.7 |
Trichococcus | 0.31 | 2.18 | 1.1 | 0.18 | 1.18 | 0.62 | 10.76 | 0.67 | 0.01 | 61.01 |
Campylobacter | 3.74 | 3.79 | 7.1 | 0 | 5.74 | 15.94 | 0.07 | 0.27 | 0 | 0.02 |
Anaerococcus | 0.43 | 0.07 | 1.75 | 0.35 | 0.27 | 0.37 | 15.77 | 0.75 | 0.11 | 15.1 |
Catonella | 0 | 0 | 0 | 0 | 8.91 | 9.87 | 0 | 0.14 | 0 | 0 |
Fusobacterium | 1.71 | 0.3 | 16.22 | 0.02 | 0 | 0 | 0.01 | 0.11 | 0.01 | 0 |
Peptoniphilus | 4.14 | 3.81 | 1.62 | 0.24 | 1.56 | 3.91 | 0.27 | 0.58 | 0.01 | 1.7 |
NC, not collected.