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. 2021 Apr 19;12:641378. doi: 10.3389/fimmu.2021.641378

Figure 3.

Figure 3

Lymphocyte non-specific function detection for distinguishing between ATB and LTBI. (A) Scatter plots showing the results of CD4+ T cell non-specific function, CD8+ T cell non-specific function, and NK cell non-specific function in ATB patients (n=49), LTBI individuals (n=64), and HC (n=95). Bars indicated the medians and interquartile ranges. ***P < 0.001; ns, no significance (Mann-Whitney U test). (B) ROC analysis showing the performance of CD4+ T cell non-specific function, CD8+ T cell non-specific function, and NK cell non-specific function in discriminating ATB patients from LTBI individuals. ATB, active tuberculosis; LTBI, latent tuberculosis infection; HC, healthy controls; ROC, receiver operating characteristic; AUC, area under the curve; CI, confidence interval.