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. 2021 Apr 19;12:641378. doi: 10.3389/fimmu.2021.641378

Table 2.

Demographic and clinical characteristics of ATB patients with negative and positive T-SPOT results.

Variables ATB with negative T-SPOT result (n = 10) ATB with positive T-SPOT result (n = 39) P*
Age, years 52 (26-56) 48 (29-61) 0.673
Sex, male, % 5 (50%) 22 (56.41%) 0.716
TB history 3 (30%) 8 (20.51%) 0.521
Presence of BCG scar 4 (40%) 17 (43.59%) 0.838
Underlying condition or illness
 Diabetes mellitus 2 (20%) 5 (12.82%) 0.563
 Solid tumor 1 (10%) 4 (10.26%) 0.981
 Hematological malignancy 0 (0%) 1 (2.56%) 1
 End-stage renal disease 1 (10%) 3 (7.69%) 1
 Liver cirrhosis 0 (0%) 2 (5.13%) 1
 Organ transplantation 1 (10%) 1 (2.56%) 0.37
Immunosuppressive condition 2 (20%) 5 (12.82%) 0.563
Positive mycobacterial culture 8 (80%) 32 (82.05%) 0.881
Positive GeneXpert MTB/RIF 7 (70%) 29 (74.36%) 0.781

ATB, active tuberculosis; BCG, bacille Calmette-Guérin; TB, tuberculosis

*Comparisons were performed between these two groups using Mann-Whitney U test, chi-square test, or Fisher’s exact test. Patients who underwent organ transplantation, chemotherapy, or took immunosuppressants within 3 months. Data were presented as medians (25th-75th percentiles), or numbers (percentages).