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. 2021 Apr 27;12(2):e00085-21. doi: 10.1128/mBio.00085-21

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Copyright © 2021 Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 5 — Characterization of the effector function of CD4 and CD8 T cells in the PBMCs of individuals recovering from COVID-19. PBMCs of UI (n = 5) and CI (n = 5) were either stimulated with anti-CD3 and anti-CD28 antibodies (αCD3/CD28) or left unstimulated (UC) and cultured for 5 days. The percentages of Ki67 (A)-, IFN-γ (B)-, IL-2 (C)-, and TNF-α (D)-positive CD4 (left) and CD8 (right) T cells were analyzed by flow cytometry. CI, COVID-19-convalescent individuals; UI, SARS-CoV-2-unexposed individuals. Statistically significant differences are indicated by asterisks (*, <0.05; **, <0.01; nonparametric Mann-Whitney test).