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. 2021 Mar 30;12(2):e00279-21. doi: 10.1128/mBio.00279-21

FIG 5.

FIG 5

Size distributions of BMDM-EVs under different cryptococcal stimulations. The major size distribution of BMDM-EVs was around 40 to 60 nm in diameter. (A) Representative TEM image of BMDM-EVs. (B and C) Frequency distributions of live-BM-EVs (EVs from live C. neoformans-infected activated BMDMs) analyzed by DLS (B) (n = 192) and TEM (C) (n = 59). (D and E) Frequency distributions of Hk-BM-EVs (EVs from heat-killed C. neoformans-infected activated BMDMs) analyzed by DLS (D) (n = 329) and TEM (E) (n = 61). (F and G) Frequency distributions of non-BM-EVs (EVs from activated BMDMs without C. neoformans infection) analyzed by DLS (F) (n = 289) and TEM (G) (n = 74). HV, high voltage.