TABLE 2.

Analysis of enrichment of integration into specific genes in vivo^a

Chromosome	Gene nameb	Independent integrations ex vivoc	Independent integrations in CHER cohort pre-ART	Adjusted P valued	Independent integrations in CHER cohort on ART	Adjusted P valued
17	STAT5B	562	29	0.14	37	4.0E−29
6	BACH2	132	31	8.9E−17	16	2.7E−15
All	All other genes	334,920	6,979	>0.05	1,149	>0.05

^aData are shown only for integrations into genes and when at least 1 integration was detected in both libraries.

^bGenic coordinates mapped to hg19.

^cEx-vivo data set contains integration sites from CD8-depeleted PBMCs from two healthy donor patients infected and phytohemagglutinin (PHA)-stimulated ex vivo.

^dAdjusted P value determined by Fisher’s exact test with post hoc Benjamini-Hochberg correction.