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Intraperitoneal inoculation of BSE isolates in mice overexpressing murine and bovine PrP
| Mice | Mean survival time, dpi (n/n0)a |
|
|---|---|---|
| Cattle BSE | Mouse BSE | |
| TgMo/− | 679 ± 57 (6/6) | 279 ± 9 (6/6) |
| TgMo/TgBo | 709 ± 70 (6/6) | 272 ± 15 (6/6) |
| TgBo/− | 457 ± 54 (6/6) | >650 (6/6) |
Survival time is indicated as mean number of days postinoculation (dpi) ± SD for all the mice that scored positive for PrPres. n/n0, number of diseased PrPres-positive animals/inoculated animals.
