Comparison 5. Sensitivity analyses on quality of studies ‐ impact of missing data (best & worst case scenarios) ‐ incidence of depression: pharmacological intervention versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
5.1 best case scenario	10	1400	Odds Ratio (M‐H, Random, 95% CI)	0.15 [0.09, 0.24]
5.1.1 post‐intervention	9	1045	Odds Ratio (M‐H, Random, 95% CI)	0.13 [0.07, 0.24]
5.1.2 short‐term	1	28	Odds Ratio (M‐H, Random, 95% CI)	0.31 [0.06, 1.51]
5.1.3 medium‐term	3	327	Odds Ratio (M‐H, Random, 95% CI)	0.16 [0.06, 0.43]
5.2 worst case scenario	10	1400	Odds Ratio (M‐H, Random, 95% CI)	1.63 [0.97, 2.73]
5.2.1 post‐intervention	9	1045	Odds Ratio (M‐H, Random, 95% CI)	1.35 [0.74, 2.44]
5.2.2 short‐term	1	28	Odds Ratio (M‐H, Random, 95% CI)	1.07 [0.23, 4.89]
5.2.3 medium‐term	3	327	Odds Ratio (M‐H, Random, 95% CI)	4.81 [0.92, 25.29]