Griffiths 2016.

Study characteristics
Methods	Randomised clinical trial
Participants	9 participants in Australia Inclusion and exclusion criteria: no data provided
Interventions	2‐arm trial Intervention (n = 4): periodic fasting. 3 very low energy diet (VLED) shakes a day (~2,500 kJ/day) on any 2 days a week and to eat to appetite on other days. Comparator (n = 5): participants randomised to continuous energy restriction were instructed to reduce their energy intake by 30% everyday in accordance with the Australian Guide to Healthy Eating
Outcomes	Body weight, BMI, waist circumference, lipid profile, glucose, HbA1c
Notes	Type of paper: abstract only Funding: no data provided
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Abstract only and method of randomisation not stated in abstract.
Allocation concealment (selection bias)	Unclear risk	Not stated.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Since this trial was a dietary intervention study, it was not feasible for participants or all study personnel to be blinded to the group assignment
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not stated.
Incomplete outcome data (attrition bias) All outcomes	High risk	1 out of the 5 participants (20%) dropped out in IF arm.
Selective reporting (reporting bias)	Unclear risk	Unclear from abstract.
Other bias	Unclear risk	Not stated.