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. 2021 Jan 29;2021(1):CD013496. doi: 10.1002/14651858.CD013496.pub2

Moro 2016.

Study characteristics
Methods Randomised controlled trial
Participants 34 participants based in the USA who have performed resistance training continuously for the last 5 years.
Inclusion and exclusion criteria: the criteria for entering the study were that participants must have performed resistance training continuously for at least 5 years (training 3–5 days/week with at least 3 years experience in split training routines), be presently engaged in regular resistance training at the time of recruitment, be life‐long steroid free, and have no clinical problems that could be aggravated by the study procedures.
Interventions 2‐arm trial
Intervention (n = 17): time restricted feeding (16 hours fasting, 8 hours feeding)
Comparator (n = 17): ad libitum feeding/normal diet
Outcomes Lipid profile
Notes Other: data presented as percentage changes. Authors contacted for absolute changes but no response was given. Therefore, data unfortunately not included in quantitative analysis.
Funding: this research was conducted with authors’ institutional founds
Type of paper: full‐text publication
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Participants were randomly assigned to a time‐restricted feeding group (TRF; n = 17) or standard diet group (ND; n = 17) through computer‐generated software.
Allocation concealment (selection bias) Unclear risk Although it was stated quote: "the research staff conducting outcome assessments was unaware of the assignment of the subjects (i.e. a single blind design)", it was not indicated how the assignment sequence was concealed.
Blinding of participants and personnel (performance bias)
All outcomes High risk Since this trial was a dietary intervention study, it was not feasible for participants or all study personnel to be blinded to the group assignment.
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Quote: "The research staff conducting outcome assessments was unaware of the assignment of the subjects (i.e. a single blind design)."
Incomplete outcome data (attrition bias)
All outcomes Unclear risk There was no information provided regarding dropout or the number of completers.
Selective reporting (reporting bias) Unclear risk Unclear.
Other bias Low risk Nothing to note.