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. 2021 Jan 29;2021(1):CD013496. doi: 10.1002/14651858.CD013496.pub2

Ntr 2009.

Methods Randomised controlled trial
Participants Inclusion criteria:
1. Lean healthy male volunteers;
2. Age 18 ‐ 35 years;
3. BMI 20‐25 kg/m2;
4. Stable weight three months prior to study inclusion;
5. Normal oral glucose tolerance test (OGTT) using the ADA‐criteria.
Interventions 1. Two weeks standard diet;
2. Two weeks of intermittent fasting. After these two weeks, a study day as previously described will follow where after volunteers change diet (standard vs IF, or IF vs standard).
Outcomes Primary outcome: insulin sensitivity of glucose metabolism.
Secondaryoutcome: insulin sensitivity of lipid and protein metabolism.
Notes It is unclear from the information above that the intervention meets our predefined criteria.