SLCTR/2018/001.

Study name	Effectiveness of time restricted diet versus a diet taken throughout the day on weight reduction and metabolic parameters in obese individuals.
Methods	Randomised controlled trial
Participants	Inclusion criteria 1.Men and women aged 18‐50 years with a BMI of 25 kg/m2 to 35 kg/m2. Exclusion criteria 1. Patients with identified secondary cause for obesity 2. Inability to adhere to the suggested meal plan and exercise regimen. 3. Any underlying medical condition which can interfere with the proposed dietary plan and exercise regimen (i.e. diabetes mellitus, Cushing’s disease, rheumatoid arthritis and osteoarthritis of knees.) 4. Patients who are on drugs which can interfere with the proposed diet (i.e. prednisolone) 5. Women who are pregnant or breast feeding 6. Patients with diagnosed psychiatric disorder.
Interventions	One group (Group 1) will be given the choice to take the restricted calorie intake at any time during the day. Group 2 will be advised to take the calorie restricted diet during a twelve hour period (e.g. from 6 am to 6 pm).
Outcomes	Weight [At baseline and at the end of 3 months] Fasting blood sugar level [At baseline and at the end of 3 months] HbA1C level [At baseline and at the end of 3 months] Lipid Profile [At baseline and at the end of 3 months] Alanine transaminase level [At baseline and at the end of 3 months]
Starting date	2018‐01‐02
Contact information	noelsomasundaram@gmail.com
Notes

ADF: alternate day fasting; BMI: body mass indexCER: continuous energy restriction; CRP: C‐reactive protein; CVD: cardiovascular disease; DBP: diastolic blood pressure; HbA1c: glycated haemoglobin; HDL: high density lipoprotein; IER: intermittent energy restriction; IF: intermittent fasting; LDL: low‐density lipoprotein; OCTT: oral glucose tolerance test; SBP: systolic blood pressure; TC: total cholesterol; TG: triglycerides; TRF: time‐restricted feeding.