Table 3. Expression of lens cytoskeletal and membrane protein genes.
Age of onset in hours post fertilization (hpf) determined using a publically available whole embryo RNA- Seq dataset (EBI). Location of expression is determined from our single cell RNA-Seq data.
| ZFIN Gene name | Ensemble ID | Expression onset (hpf) | Expression location |
|---|---|---|---|
| Cytoskeletal protein genes | |||
| bfsp1 | 00000074919 | 19 | Lens fiber and epithelial cells |
| bfsp2 | 00000011998 | 19 | Lens fiber cells |
| sptan 1 | 00000019231 | 0 | Lens fiber and epithelial cells, cranial ganglia, melanophores, xanthophores, endothelia and notochord |
| sptbn 1 | 00000102883 | 0 | Lens fiber and epithelial cells, cranial ganglia, melanophores, xanthophores, endothelia and notochord |
| sptbn2 | 00000053956 | 0 | Lens fiber and epithelial cells, nervous tissue |
| sptbn5 | 00000097683 | 30 | Lens fiber and epithelial cells, kidney |
| sptb | 00000030490 | 16 | Red Blood Cells |
| vim | 00000010008 | 2.25 | Lens fiber and epithelial cells, widespread |
| Membrane associated protein genes | |||
| cdh2 | 00000018693 | 0 | Lens fiber and epithelial cells, widespread |
| cx23 | 00000054150 | 0.75 | Lens fiber and epithelial cells |
| cx43 | 00000041799 | 0 | Lens fiber and epithelial cells, widespread |
| gja3 | 00000021889 | 19 | Lens fiber cells |
| gja8a | 00000069451 | 30 | Lens fiber and epithelial cells |
| gja8b | 00000015076 | 19 | Lens fiber and epithelial cells |