Skip to main content
. 2021 Apr 28;2021(4):CD013535. doi: 10.1002/14651858.CD013535.pub2

Comparison 1. Corticosteroids versus standard care.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Length of hospital stay 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.2 Duration of time requiring antibiotics 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.3 Proportion of participants who required surgical intervention 1   Risk Ratio (IV, Fixed, 95% CI) Subtotals only
1.4 Pain 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.4.1 Day 0 1 22 Mean Difference (IV, Fixed, 95% CI) 0.00 [‐0.38, 0.38]
1.4.2 Day 3 1 22 Mean Difference (IV, Fixed, 95% CI) ‐0.20 [‐1.02, 0.62]
1.5 Periorbital edema 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.5.1 Day 0 1 22 Mean Difference (IV, Fixed, 95% CI) 0.00 [‐0.69, 0.69]
1.5.2 Day 3 1 22 Mean Difference (IV, Fixed, 95% CI) 0.10 [‐0.41, 0.61]
1.5.3 Day 7 1 22 Mean Difference (IV, Fixed, 95% CI) 1.20 [0.62, 1.78]
1.5.4 Day 10 1 22 Mean Difference (IV, Fixed, 95% CI) 0.80 [0.44, 1.16]
1.6 Amount of proptosis (mm) 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.6.1 Day 0 1 22 Mean Difference (IV, Fixed, 95% CI) ‐0.20 [‐1.84, 1.44]
1.6.2 Day 3 1 22 Mean Difference (IV, Fixed, 95% CI) 0.00 [‐1.38, 1.38]
1.6.3 Day 7 1 22 Mean Difference (IV, Fixed, 95% CI) 1.10 [‐0.05, 2.25]
1.6.4 Day 10 1 22 Mean Difference (IV, Fixed, 95% CI) 1.00 [0.25, 1.75]
1.6.5 Day 14 1 22 Mean Difference (IV, Fixed, 95% CI) 1.00 [0.44, 1.56]
1.7 Conjunctival chemosis 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.7.1 Day 0 1 22 Mean Difference (IV, Fixed, 95% CI) ‐0.30 [‐0.93, 0.33]
1.7.2 Day 3 1 22 Mean Difference (IV, Fixed, 95% CI) 0.30 [‐0.09, 0.69]
1.8 Preservation of visual acuity at the end of the study period 1   Risk Ratio (IV, Fixed, 95% CI) Subtotals only
1.9 Exposure keratopathy 1   Risk Ratio (IV, Fixed, 95% CI) Subtotals only
1.10 Other adverse events 1   Risk Ratio (IV, Fixed, 95% CI) Subtotals only