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. 2021 Apr 29;2021(4):CD008189. doi: 10.1002/14651858.CD008189.pub3

Summary of findings 4. Preconception lifestyle advice on smoking compared to routine care or attention control for people with infertility.

Preconception lifestyle advice on smoking compared to routine care or attention control for people with infertility
Patient or population: smoking people with infertility
Setting: university/hospital
Intervention: preconception lifestyle advice on smoking
Comparison: routine care
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) №. of participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with routine care or attention control Risk with preconception lifestyle advice on smoking
Live birth or ongoing pregnancy No studies reported on this outcome
Adverse events No studies reported on this outcome
Miscarriage No studies reported on this outcome
Reported behavioural changes: smoking In the single study in this comparison, study authors concluded, "There were no significant differences in the mean delta stage‐of‐change or 12‐month rate of maintained cessation". The rate of maintained cessation was not reported separately for intervention and control groups
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval.
GRADE Working Group grades of evidence.
High quality: further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: we are very uncertain about the estimate.