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. 2021 Apr 29;2021(4):CD008189. doi: 10.1002/14651858.CD008189.pub3

1. Additional data on lifestyle behavioural changes not reported according to definitions in the review methods.

Comparison 1. Preconception lifestyle advice on a combination of any of the following topics: weight, diet, vitamin and mineral intake, alcohol intake, caffeine intake, physical activity, smoking, and/or other substance abuse compared to routine care or attention control
  Reported behavioural changes in diet
Oostingh 2020 Number of participants with adequate vegetable intake (> 200 grams/d) at 6 months
Women:
124/299 in experimental group
89/313 in control group
RR 1.46, 95% CI 1.17 to 1.82
Men:
40/103 in experimental group
31/113 in control group
RR 1.42, 95% CI 0.96 to 2.08

Number of participants with adequate fruit intake (> 2 pieces/d) at 6 months
Women:
207/299 in experimental group
182/311 in control group
RR 1.18, 95% CI 1.05 to 1.33
Men:
67/103 in experimental group
46/111 in control group
RR 1.57, 95% CI 1.21 to 2.04
Ng 2018 Fruit intake in pieces/d at 3 months (mean ± SD)
2.82 ± 1.9 in experimental group (n = 131)
2.02 ± 1.7 in control group (n = 133)
MD 0.80, 95% CI 0.36 to 1.24
Comparison 2. Preconception lifestyle advice on weight compared to routine care
  Reported behavioural changes in diet
Belan 2019 Composite score: healthy eating index in points at 6 months (mean ± SD)
18.2 ± 13.7 in experimental group (n = 46)
5.3 ± 12.4 in control group (n = 51)
MD 12.90, 95% CI 7.68 to 18.12
Mutsaerts 2016 Sugary drinks in glasses/d at 6 months (mean ± SD)
0.59 ± 0.2 glasses/d in experimental group (n = 88)
0.99 ± 0.3 glasses/d in control group (n = 128)
MD ‐0.41, 95% CI ‐0.47 to ‐0.34

Savoury snacks in handfuls/week at 6 months (mean ± SD)
2.17 ± 0.73 handfuls/week in experimental group (n = 100)
2.32 ± 0.81 handfuls/week in control group (n = 139)
MD ‐0.15, 95% CI ‐0.35 to 0.05

Sweet snacks in portions/week at 6 months (mean ± SD)
1.725 ± 0.32 portion/week in experimental group (n = 99)
2.72 ± 0.79 portion/week in control group (n = 136)
MD ‐1, 95% CI ‐1.14 to ‐0.85
  Reported behavioural changes in physical activity
Belan 2019 Total leisure activity energy expenditure in kcal/kg/d at 6 months (mean ± SD)
0.77 ± 1.63 in experimental group (n = 46)
0.17 ± 1.26 in control group (n = 51)
MD 0.60, 95% CI 0.02 to 1.18
Comparison 3. Preconception lifestyle advice on alcohol intake compared to routine care
  Reported behavioural changes in alcohol intake
Rossi 2013 Decrease in number of drinks on a drinking day (mean ± SD)
1 ± 1 in experimental group (n = 16)
0.4 ± 1 in control group (n = 21)
MD 0.60, 95% CI ‐0.05 to 1.25

Decrease in % of drinking days in past 6 months (mean ± SD)
0.2 ± 0.3 in experimental group (n = 16)
0.1 ± 0.2 in control group (n = 21)
MD 0.10, 95% CI ‐0.07 to 0.27

Decrease in number of weeks drinking above the safety daily limit in the past 6 months(mean ± SD)
5.6 ± 9 in experimental group (n = 16)
1.7 ± 3.5 in control group (n = 21)
MD 3.90, 95% CI ‐0.76 to 8.56

Decrease in number of binges in the past 6 months (mean ± SD)
14.5 ± 44.4 in experimental group (n = 16)
1.2 ± 4.5 in control group (n = 21)
MD 13.30, 95% CI ‐8.54 to 35.14
Comparison 4. Preconception lifestyle advice on alcohol intake compared to routine care
  Reported behavioural changes in smoking
Hughes 2000 Delta stage‐of‐change = difference in stage of motivation to change smoking behaviour (mean)
Experimental group (mean): 0.31 (no SD reported) (n = 47)
Control group (mean): 0.26 (no SD reported) (n = 47)

Rate of maintained cessation
"Rate of maintained cessation rose from 4% to 24% (P < 0.001)" (experimental and control groups reported together)
No further data provided

CI: confidence interval.

MD: mean difference.

RR: risk ratio.

SD: standard deviation.