1. Multimorbidity intervention components.

Author Year	Professional	Participant	Organisational			Effect of intervention on primary outcome
			Case management or coordination of care	Reorganisation of care/team working	New team member
Predominantly organisational
Barley 2014	Nurse training	Participant information Prioritisation to create goals and health plan	Case manager provided personalised care	Regular planned participant visits Weekly team meetings	Nurse case manager	Pilot study and primary outcome was feasibility and deemed successful
Bogner 2008		Individualised programme	Case manager	Regular planned participant visits		Improved blood pressure control and depression scores
Boult 2011	Nurse training	Individual management plans Support for self‐management	Guided care nurses coordinated care	Guided care 'pods' consisting of nurse and PCP Monthly monitoring of participants		No impact on healthcare utilisation
Coventry 2015	Practice team training	Personalised goals and participant workbooks		Collaborative care using stepped care protocols Joint consultation between participant, psychologist and practice nurse	Psychologist Supervision and input from team psychiatrist	Modest reduction in depression scores
Hogg 2009		Individualised care plans		Multidisciplinary team‐based management with home based assessment Medication review	Pharmacist	Modest improvements in quality of chronic care delivery
Katon 2010		Individualised management plans and targets Support for self‐management		Team‐based care Stepped care treatment protocols Weekly team meeting	Psychologist and psychiatrist supported depression care	Improvements in composite outcome of glycaemic control, blood pressure, lipids and depression scores
Kennedy 2013	Practice training	Support for self‐management Participant guidebooks		Systems‐based approach to self‐management support with practice supports and links made with related local services		No intervention effect noted
Krska 2001		Individualised pharmaceutical care plans		Practice team‐implemented care plans	Pharmacist undertook medication review and devised pharmaceutical care plans	Reduction in pharmaceutical care issues
Martin 2013	Training for community psychologists	Cognitive behavioural therapy sessions		Psychological care programme designed for headache and depression	Community psychologists	Reduced headaches and improved depression scores
Morgan 2013	Practice nurse training	Support for self‐management Goal setting Individualised care plans	Nurse case manager	Quarterly reviews with practice nurse with GP stepping up care as needed		Improved depression scores
Sommers 2000		Risk reduction plan		Team based care with home assessment followed by team discussion, treatment plan and targets	Social worker	Reduced hospitalisation
Wakefield 2012		Participation in home telehealth monitoring	Nurse case manager using telehealth monitoring and treatment algorithms			Improved blood pressure, no effect on glycaemic control
Predominantly Patient‐oriented interventions
Eakin 2007		Support for self‐management with focus on diet and physical activity		Regular visits and follow‐up telephone calls	Health educator	Improvements in diet but not in physical activity
Garvey 2015	Occupational therapist (OT) training	OT‐led, group‐based support for self‐management programme (6 weeks) Goal setting and peer support		GP and primary care team referral	OT with input from physiotherapist and pharmacist	Improvements in activity participation
Hochhalter 2010	Training for coaches running intervention	Patient Engagement workshop (x1)		Two follow‐up phone calls	Coach who delivered workshop	No effect on outcomes
Lorig 1999	Training for volunteer lay group leaders	Chronic Disease Self Management Support Programme (six sessions) Peer support			Volunteer lay group leaders supported by study team	No primary outcome specified. Multiple outcomes reported with mixed effects
Lynch 2014		Diabetes self management support groups (18 sessions) Peer support Goal setting and behaviour skills training			Dietician led groups	No effect on primary outcome of weight reduction

The predominant intervention component is highlighted in bold text for each study

No study contained a financial‐type intervention element