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. 2021 Jan 15;2021(1):CD006560. doi: 10.1002/14651858.CD006560.pub4

Bogner 2008.

Study characteristics
Methods Randomised controlled trial
USA
Participants 64 participants aged 50 years and older with hypertension and depression (defined as a diagnosis of depression or prescription of antidepressant within the past year)
Integrated care manager and 12 family physicians in primary care clinic
Interventions Integration of depression and hypertension treatment coordinated by integrated care manager; individualised program comprising three 30 minute in‐person sessions with participants and two 15 minute follow‐up phone calls
Outcomes Primary and secondary (no distinction specified):
Depression scores (Centre for Epidemiological Studies depression scale (CES‐D))
Blood pressure
Medication (% adherent to antidepressant medication; % adherent to antihypertensive medication (adherence measured using electronic measuring devices (MEMS caps))
Notes Intervention lasted 6 weeks and follow‐up 2 weeks later
Comparison: usual care
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Paper states "patients were randomly assigned"
Allocation concealment (selection bias) Unclear risk Not stated in text
Blinding (performance bias and detection bias)
All outcomes Unclear risk Automated measurement devices were used but authors don't specifically state that outcome assessors were blinded
Incomplete outcome data (attrition bias)
All outcomes Low risk 100% follow‐up reported
Selective reporting (reporting bias) Low risk None apparent
Other bias Low risk None apparent
Protection against contamination Low risk 25% control consultations monitored to check for contamination
Reliable primary outcomes Low risk Validated measures and automated tests
Baseline measurement Low risk Groups comparable at baseline