. 2021 Feb 17;65(3):e01370-20. doi: 10.1128/AAC.01370-20

TABLE 2.

IC₅₀ and worm burden reduction values of synthesized analogs^a

Compound	IC₅₀ (µM)		SI	WBR (%)
Compound	Adult S. mansoni	L6 cells	SI	WBR (%)
27	0.31	5.7	18.3	9.3
29	0.28	12.5	44.6	46.4
30	0.19	1.7	8.9	12.5
Praziquantel	0.1^b	>96^b	>960^b	94.1^c

SI, selectivity index (IC_50,L6/IC_50,_{S. mansoni}); WBR, worm burden reduction.

Reference 26.

Reference 29.