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. 2021 Feb 17;65(3):e01988-20. doi: 10.1128/AAC.01988-20

TABLE 8.

MIC and MFC values with fungicidal or fungistatic activity indicated for SCY-247 and IBX against the individual C. auris isolatesa tested

Isolate identifierb SCY-247
 IBX
MICc MFCc Antifungal MICc MFCc Antifungal
Activity Activity
35364Am,M 0.125 1 Static 0.125 1 Static
35366Am,M 0.25 1 Cidal 0.5 1 Cidal
35367Am,F,M 0.5 1 Cidal 0.25 2 Static
35368Am,C,F,M 0.5 4 Static 0.5 8 Static
35370Am, F,M 0.5 8 Static 0.5 8 Static
35371Am,F,M 0.5 8 Static 0.5 8 Static
35372Am,M 0.5 4 Static 0.25 2 Static
35373Am,C,F,M 0.5 4 Static 0.25 4 Static
35374Am,C,F,M 0.5 4 Static 0.25 4 Static
35375Am,F,M 0.5 4 Static 0.25 4 Static
35376Am,M 0.5 2 Cidal 0.5 2 Cidal
35377Am,C,M 0.5 4 Static 0.25 2 Static
35378C,M 1 4 Cidal 0.5 4 Static
35379Am 0.5 4 Static 0.5 2 Cidal
35645 0.125 0.5 Cidal 0.125 2 Static
35646C,F 0.5 2 Cidal 0.25 4 Static
35647F,V 0.5 4 Static 0.5 4 Static
35648Am,F,V 0.5 2 Cidal 0.5 4 Static
35649Am,F,V 0.25 2 Static 0.25 4 Static
35650Am,F,V 0.25 4 Static 0.25 4 Static
35651C,F 0.5 2 Cidal 0.5 4 Static
35652Am,C,F,V 0.5 4 Static 0.5 1 Cidal
35653An,C,F,V 0.5 4 Static 0.5 8 Static
35654An,F,V 0.5 2 Cidal 0.25 4 Static
37101Am 0.5 4 Static 0.25 4 Static
37102Am 0.5 4 Static 0.5 4 Static
37103Am 0.25 2 Static 0.25 4 Static
37104Am 0.5 4 Static 0.5 4 Static
37432 0.5 2 Cidal 0.5 4 Static
37433 0.25 4 Static 0.25 4 Static
37434 0.25 2 Static 0.5 4 Static
38684 0.5 2 Cidal 0.5 4 Static
38883Am 0.5 4 Static 0.5 4 Static
39307Am 1 4 Cidal 2 8 Cidal
39308 0.5 4 Static 0.5 4 Static
39309 0.5 4 Static 0.25 4 Static
39414Am 0.25 4 Static 0.5 4 Static
39415F 0.125 2 Static 0.25 1 Cidal
39416Am,C,M,F,V 0.5 4 Static 0.5 4 Static
39417AmF 0.5 2 Cidal 0.5 4 Static
39418AmF 1 4 Cidal 0.5 4 Static
39419Am,C,F,V 0.5 4 Static 0.25 4 Static
39420Am,F,V 0.25 4 Static 0.5 8 Static
41527 0.06 0.5 Static 0.06 0.25 Cidal
a

n = 44.

b

Am, amphotericin B; An, anidulafungin; C, caspofungin; F, fluconazole; M, micafungin; V, voriconazole.

c

µg/ml.