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Metabolite-mediated potentiation of NIT activity with different carbon sources. Cultures of E. coli grown to stationary phase in MOPS plus glucose were treated with DMSO (control), 250 μg/ml NIT, and 10 mM mannitol with or without NIT (A) or 10 mM lactate with or without NIT (B). CFU per milliliter were determined at the indicated time points. *, P < 0.05 (t test), comparing NIT with mannitol plus NIT (A) or NIT with lactate plus NIT (B).
