. 2021 Feb 17;65(3):e01858-20. doi: 10.1128/AAC.01858-20

TABLE 1.

Characteristics of constructed strains^a

Strain pair	Strain	RpsL	GyrA	Fitness cost of gyrA mutation (%)	MIC (mg/liter)
Strain pair	Strain	RpsL	GyrA	Fitness cost of gyrA mutation (%)	Str	Cip	Ctx	Tet
GyrA^wt	DA26187	K43T	wt		1,024	0.016	8	1
GyrA^D87Y	DA26192	K43T	D87Y	1.4	1,024	0.125	8	0.5
GyrA^wt	DA28261	K43R	wt		1,024	0.016	16	1
GyrA^S83L	DA28400	K43R	S83L	0.2	1,024	0.25	16	2

Str, streptomycin; Cip, ciprofloxacin; Ctx, cefotaxime; Tet, tetracycline; wt, wild type.